May/June 2010




Confronting the Clinical Challenges of Frontotemporal Dementia

A look at FTD’s symptoms, pathophysiology, subtypes, as well as the latest from imaging studies.

By Zac Haughn, Senior Associate Editor


Case Report: Leber Hereditary Optic Neuropathy in a 60-Year-Old Man with Vitamin B12 Deficiency

LHON should be considered as a diagnosis in patients, regardless of age, with unexplained bilateral optic neuropathy and central vision loss.

By Darby D. Miller, MD, Craig E. Geist, MD, and Charles J. Macri, MD

Neurology Clinical Trials in the Community Hospital Setting

A significant trend, encouraged by NIH, is expanding clinical research to community hospitals with potential benefits for patients and clinicians.

By David M. Brown, MD, and Laura Whitaker, RN

Editor’s Message

By Paul Winnington

Dementia Insights: The Role of Cognitive Fluctuations and Impaired Episodic Memory in the Diagnosis of Dementia: New Considerations

Studies suggest that the presence of cognitive fluctuations and abnormalities in episodic memory and delayed recall can occur in several dementias.

By Ronald Devere, MD

Expert Opinion: Neuropsychological Impairments In Females with Primary Sjögren’s Syndrome: New Insights

The pSS literature has reported varying degrees of central nervous system involvement in individuals with this condition and secondary cognitive deficits associated with the disease.

By Tiffany Jennings, PsyD; Frederick Vivino, MD; Steven Mandel, MD; Kenneth Goldberg, PsyD; Edward Maitz, PhD; Bret Boyer, PhD

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About Practical Neurology

Launched in 2002, Practical Neurology is a publication uniquely dedicated to presenting current approaches to patient management, synthesis of emerging research and data, and analysis of industry news with a goal to facilitate practical application and improved clinical practice for all neurologists. Our straightforward articles give neurologists tools they can immediately put into practice.