November/December 2013




A Closer Look at Parkinson’s Therapies

An update by Practical Neurology

By Zac Haughn, Senior Associate Editor

Parkinson’s Study Looks for Prodromal and Disease Progression Biomarkers

A Summary by the Parkinson’s Progression Marker’s Initiative (PPMI)

Focused Ultrasound for Parkinson’s Tremor: An Update

Data to date suggest that focused ultrasound may provide a non-invasive, non-pharmacologic option to treat the tremor of PD.

A Q&A with Binit B. Shah, MD

Exploring Expanded Labeling for DBS for Parkinson’s

Expanded labeling is based on data showing an improvement in quality of life and longer-term data.

A Q&A With William Marks, MD


Beyond Altered Mental Status: LOL AMEN

A laughably easy test to remember.

By Gary L. Cohen, MD

A Practical Evaluation of Migraine Trigger Site Deactivation Surgery

An analysis of the data casts doubt on the purported benefits of MTSDS.

By Paul G. Mathew, MD, FAHS

An Update on the Management of Chronic Migraine

In 1672, Thomas Willis provided the first description of chronic migraine (CM) when he reported the case of the philosopher, Anne, Viscountess Conway, who was also treated by William Harvey and Robert Boyle without success.1-4 Has our treatment of chronic migraine since improved?

By Randolph W. Evans, MD

In the Pipeline A New Image Search: PET Amyloid Imaging Agent is Yielding Results

Piramal Imaging shared promising results from five studies evaluating the company’s PET amyloid imaging agent (florbetaben F18*) at the 2013 Alzheimer’s Association International Conference this summer.


Expert Opinion Cauda Equina Syndrome: A Case Report and Review of the Literature

By Ahmed Al-Badri, MD; Jean Jacques Mbabuike, MD; David A. Porter, MD; Pierce J. Ferriter, MD; and Steven Mandel, MD

Video Case Solution

Solution: Migrant sensory neuritis of Wartenberg

Last month’s case presented recurrent acute focal pain and persistent numbness in a middle-age woman.

By Aziz Shaibani, MD, FACP, FAAN

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About Practical Neurology

Launched in 2002, Practical Neurology is a publication uniquely dedicated to presenting current approaches to patient management, synthesis of emerging research and data, and analysis of industry news with a goal to facilitate practical application and improved clinical practice for all neurologists. Our straightforward articles give neurologists tools they can immediately put into practice.