In this Issue
Seeking Breakthrough Treatments
GUEST MEDICAL EDITOR’S PAGE
The challenges we must overcome to find breakthrough treatments in neurology are many and the potential is great.
By Shamik Bhattycharyya, MD, MS
MULTIPLE SCLEROSIS MINUTE
Functional imaging studies suggest neurogenic overactive bladder in people with MS may differ from idiopathic overactive bladder.
By Daniel Kantor, MD, FAAN, FANA
The stigma associated with words headache and migraine carries over to those stricken in a way that no other neurologic condition does.
By Peter McAllister, MD
SEEKING BREAKTHROUGH TREATMENTS
A roundtable discussion with Gregory Went, PhD, Adamas Pharmaceuticals; Lynn Kramer, MD, Eisai; Paulo Fontoura, MD, PhD, Genentech/Roche; Justin Gover, BSc, MBA, GW Pharmaceuticals; Marc Kamin, MD, SK Life Sciences; and Mike Davis, BSc, MBA, UCB
A roundtable discussion with Claudia A. Chiriboga, MD, MPH; Jeffrey L. Cummings, MD, ScD; and Nir Lipsman, MD, PhD
A roundtable discussion with Chase Spurlock, PhD, IQuity; Michal Izrael, PhD, Kadimastem Ltd; Kevin Hrusovsky, Quanterix; and J. Michael Ryan, MD, Rodin Therapeutics
Biomarkers have resulted from breakthrough treatments and, in turn, provide targets for more breakthroughs.
By Neeta Garg, MD; Ye Hu, MD; and Kottil W. Rammohan, MD
Could therapies developed to stop cancers be the next breakthrough for neurodegenerative disorders?
By Mazen T. Elkurd, DO; Yasar Torres-Yaghi, MD; Laxman B. Bahroo, DO; Charbel E.-H. Moussa, MD, PhD; and Fernando L. Pagan, MD
A recently graduated resident and new professor recommends ways to attract medical students to the specialty of neurology.
By Rachel Gottlieb-Smith, MD
The evidence shines a light on the need for stroke education for both clinicians and the public.
By Neil Majmundar, MD; and Priyank Khandelwal, MD
There are 3 key steps to take when preparing for retirement.
By David B. Mandell, JD, MBA; and Andrew Taylor, CFP
A treatable cause of dementia.
By Ronald Devere, MD, FAAN
SPOTLIGHT TOPIC: PAIN
Once an uncommon controversial diagnosis, piriformis syndrome is now understood as a sciatic nerve entrapment neuropathy.
By Stuart B. Black, MD, FAAN
Carefully weigh the cost to patient in time, money, and possible pain against diagnostic benefits before referring for an EMG.
By Shivkumar C. Bhadola; and Kate M. Daniello, MD
Because laboratory and imaging studies may not be sensitive enough to detect central nervous system vasculitis, maintain a low threshold for further evaluation when clinical suspicion is high.
By Elizabeth Sharp, MD; Michael Colin, MD; Peter Sayegh, MD; Julia Blanter, MD; Jared Steinklein, MD; and Asaff Harel, MD, MSc
Answers from attendees at the American Alzheimer’s International Conference in Chicago, Illinois, July 22-26, 2018.