Alzheimer’s & Dementia
News
Seeking Breakthroughs: The Industry Perspective
September 2018—A roundtable discussion with Gregory Went, PhD, Adamas Pharmaceuticals; Lynn Kramer, MD, Eisai; Paulo Fontoura, MD, PhD, Genentech/Roche; Justin Gover, BSc, MBA, GW Pharmaceuticals; Marc Kamin, MD, SK Life Sciences; and Mike Davis, BSc, MBA, UCB
Seeking Breakthroughs—We Want You!
Shamik Bhattycharyya, MD, MS
September 2018—The challenges we must overcome to find breakthrough treatments in neurology are many and the potential is great.
Breakthrough Device Designation Granted for Digital and Adaptive Reminiscence Therapy
Wednesday, August 29, 2018—The Food and Drug Administration (FDA) has designated a digital therapy for persons with Alzheimer’s Disease (AD) as a breakthrough device. This designation, a provision…
Long-Term Safety and Efficacy of Valbenazine for Patients With Tardive Dyskinesia
Monday, August 20, 2018—Long-term results for valbenazine (Ingrezza; Neurocrine Biosciences, San Diego, CA), a treatment for patients with tardive dyskinesia (TD), are being presented at the 2018 Wor…
Funding Received for Phase 2 Trial of Xanomeline-Tropsium Chloride
Wednesday, August 08, 2018—A $42-million financing round has been completed and will be used to finance a phase 2 trial of xanomeline-tropsium chloride (KarXT; Karuna, Boston, MA) for treatment of perso…
Braintest App Has Equivalent Sensitivity and Specificity as SAGE Test for Mild Cognitive Impairment
Tuesday, August 07, 2018—There is an app (BrainTest, Columbus, OH) used to detect mild cognitive impairment (MCI). It is a clinically validated, digital version of the paper and pen Self-Administered …
Aggressive Treatment of Hypertension Promotes Healthy Brains and Hearts
Monday, July 30, 2018—Aggressive lowering of systolic blood pressure (BP) reduces the risk of mild cognitive impairment (MCI) and combined MCI and dementia. In the SPRINT trial (NCT01206062), 2 str…
Breaching the Blood-Brain Barrier: A Potential New Treatment Modality
Monday, July 30, 2018—In a small, yet groundbreaking, clinical trial, MR-guided focused ultrasound (MRgFUS) (ExablateNeuro; Insightec, Miami FL) was used to open the blood-brain barrier (BBB) safel…
