Epilepsy & Seizures

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Perampanel Has Long-Term Convulsive Seizure Freedom, Efficacy at Lower Dose, and Was Recently Approved for Children Age 4 to 12 Years

Wednesday, December 05, 2018—Recently approved for use in children, age 4 and up, monotherapy or adjunctive treatment with perampanel (Fycompa; Eisai, Woodcliff Lake, NJ) is approved for treatment of part…

Midazolam Nasal Spray Safety and Efficacy Results Reported

Tuesday, December 04, 2018—In results presented at the American Epilepsy Society’s annual meeting in New Orleans, LA, midazolam nasal spray (USL261; UCB, Atlanta, GA), a drug being investigated fo…

Clobazam Oral Film Provides a Highly Consistent and Easy-to-Give Dose

Monday, December 03, 2018—A new oral-film formulation of clobazam (Sympazan; Aquestive, Warren, NJ) was recently approved by the Food and Drug Administration (FDA) for adjunctive treatment of people wi…

Safety and Equivalency of Buccal Film Formulation of Diazepam in Peri-ictal and Interictal Periods

Sunday, December 02, 2018—In results presented at the American Epilepsy Society (AES) Annual Meeting in New Orleans, LA, bioavailability and safe administration of a buccal film formulation of 12.5 mg …

Long-Term Seizure Reduction With Responsive Neurostimulation

Sunday, December 02, 2018—At the American Epilepsy Society Annual Meeting in New Orleans, LA, results were announced from a 9-year prospective study of treatment with responsive neurostimulation (RNS) …

First Report from North American SUDEP Registry Presented

Saturday, December 01, 2018—At the annual meeting of the American Epilepsy Society, data were, for the first time, reported from the North American SUDEP Registry (NASR), a retrospective repository of me…

Cannabidiol Has Long-Term Dose-Dependent Efficacy That Does Not Impact Behavior or Depend on Type of SCNA1 Mutation

Saturday, December 01, 2018—A pharmaceutical grade, highly purified cannabidiol (CBD) (Epidiolex; Greenwich Biosciences, CA) was recently approved and made available for treatment of patients with seizur…

Progress in Research for Seizure Prediction

Friday, November 30, 2018—In the 16th Judith Hoyer Lecture on Epilepsy at the annual meeting of the American Epilepsy Society in New Orleans, Michael Privitera, MD, of the University of Cincinnati…


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