Headache & Pain

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An Update on the Management of Chronic Migraine

Randolph W. Evans, MD

November/December 2013—In 1672, Thomas Willis provided the first description of chronic migraine (CM) when he reported the case of the philosopher, Anne, Viscountess Conway, who was also treated by William Harvey and Robert Boyle without success.1-4 Has our treatment of chronic migraine since improved?

The Effects of Obesity on Brain Structure and Size

Majid Fotuhi, MD, PhD and Brooke Lubinski

July/August 2013—An examination of both the pathophysiology of the link between obesity and brain injury, and available strategies that may reverse it.

Online Bonus: Opioid Dependence: Misperceptions Abound, but Physicians Can Help

July/August 2013— Despite the prevalence of opioid dependence (addiction) -- nearly half Americans responding to recent survey said they had a perso

In the Pipeline: Nasal Oxytocin Explored for Migraines

A Q&A with David C. Yeomans, PhD

May/June 2013—Can migraine patients trust the “trust drug” to heal their pain?

Online Preview: Insights on Medication Overuse Headache

March/April 2013—An excerpt from exclusive on-line content from Practical Neurology.

Medication Overuse Headache


January/February 2013—New evidence suggests that opioid overuse headache may involve activation of glial cells, in particular astrocytes and microglia, which creates a pro-inflammatory state that leads to pain facilitation.

Pain and Gain: Reassessing Hydrocodone Prescribing

Zac Haughn, Senior Associate Editor

January/February 2013—New recommendations by an FDA committee aim to decrease opioid abuse, the group says, but will physicians and patients bear the burden of its effects?

Headache, Temporomandibular Disorders, and Bruxism: Uncovering Connections

Steven D. Bender, DDS

January/February 2013—Pain and dysfunction of the temporomandibular joints and associated structures can be a source of headache and orofacial pain.


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About Practical Neurology

Launched in 2002, Practical Neurology is a publication uniquely dedicated to presenting current approaches to patient management, synthesis of emerging research and data, and analysis of industry news with a goal to facilitate practical application and improved clinical practice for all neurologists. Our straightforward articles give neurologists tools they can immediately put into practice.