Weakness and Atrophy of Right Hand Muscles in A 47-year-old Man

A 47-year-old man presents with a 13-year history of weakness and atrophy of the right hand muscles. Thoracic outlet syndrome surgery did not help. CK level and CSF examination were normal. Cervical MRI was normal. NCS showed no conduction block. The CMAPs of the right median and ulnar nerves were reduced. Sensory responses were normal. EMG revealed diffuse chronic denervation of the right arm muscles.

At what level is the lesion likely located?
1. Motor neurons
2. Motor nerves
3. Brachial plexus
4. Axons
5. Myelin

 

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Launched in 2002, Practical Neurology is a publication uniquely dedicated to presenting current approaches to patient management, synthesis of emerging research and data, and analysis of industry news with a goal to facilitate practical application and improved clinical practice for all neurologists. Our straightforward articles give neurologists tools they can immediately put into practice.

 
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